Services

NL-OPENSCREEN will assist users with the translation of bench-top assays into assay suitable for high-throughput or phenotypic screening.

Pivot Park Screening Centre accelerates drug discovery by using their long expertise on (u)HTS and their state-of-the-art robotic equipment to run screens in 384 or 1536-well format on a high quality compound library.

NL-OPENSCREEN will assemble high-quality targeted/focused compound libraries aimed at specific target protein families that will provide higher success rates.

Screen the cellular phenotypes of compound libraries in multiple dimensions.

Activity-based proteome profiling (ABPP) is an attractive and powerful chemical biological technique that accelerates most stages of the drug discovery process.

NL-OPENSCREEN is an integral part of the pan-European EU-OPENSCREEN network.

Computational methods are routinely used in drug discovery and lead optimization projects. Within NL-OPENSCREEN ample expertise is available in the application of computational chemical biology (‘big data approaches’) and cheminformatics.

NL-OPENSCREEN has assembled ample expertise to add precise pharmacological texture to the screening results, by integrating ligand engagement / target binding kinetics into the various screening protocols.